for someone who has played Skyrim atleast 5 times, you must be freaking kidding me
By endgame, I could almost 5 shot Alduin in the face and Skyrim vampirism cure is hard ? Try Morrowind
Any shrine can cure vampirism at initial stage. And with my legendary daedric sword coupled with spellbreaker legendary and legendary daedric armor alduin was a piece of cake. If you want a real challenge try the Ebony warrior at level 80.