Yes they do have an impact... i think F-Secure is the most popular AV software in the mob market...
Their impact is of the extent of the no of viruses in mobiles today... (i think apart from Cabir nd some others there aren't any major viruses for the symbian system) so its not that much popular as PC software of course.
for most viruses u just have to delete the system files....
for some u may need to format.... adn in the wcs u may hav to flash the fone....
btw they r easy to prevent too.... cos ther r jus to ways to spread them BT or GPRS...
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