I say is a stupid question... there is no point comparing the 2....
just ask which 2 motherboards to compare....
But if i were to give an answer.... it will be MSI...
not that asus makes bad motherboards or anything... but for the same price, same chipst... same socket...
an MSI motherboard will usually have more features.... both are stable, both are durable... both are nice....
but there can be specific models by both manufacturers that can be good or bad....