I think andyiz and anand,i think u guys,in my opinion,do not need an additional antispyware,coz both trend-micro and norton is 2006 are excellent with both antivirus and spyware,and other blala..associated with it!
An i think kaspersky's 2006,does well with spyware as well...
i think if your not using a security suite..i think vijay's combiantion is excellent and prescribed by most experts,but you may switch between avg or avast,otherwise in my opinion
1.AVG+Outpost+spybot/ad-aware+ewido security(excellent with malware and spyware)
Or,if you wanna shell out bucks,
1.Kaspersky 2006+outpost...
2.Mcafee 2006+outpost+spybot
or,my simple combo
Norton internet security 2006,i am not biased but this has excellent prottection for spyware,viruses,hackers,ads,pop-ups...
Its a good al-in-one package,and only to be used with 512mb ram and upwards and 1.7ghz celeron or upwards....