let me put it this way, when you install 1600 ram the motherboard at auto will run the ram at 1333. you will have to manually increase the ram multiplier through bios to run it at 1600 and accordingly set the ram voltage to what it is rated for.
In my case, i have a phenom II x4 955 c3 and corsair 2x2 gb xms3 1600 cl9. when running the ram at 1600 everything seemed normal but then after a week or so i started to get random bsods.
since then i have run the ram at 1333 8-8-24. and have had no problems at all.
there is more to gain from cpu clocks rather than ram clocks.