Theoretically it should, but practically, it may bottleneck WD black.
I am having one Intel D915 board running with 2TB drive.. Runs fine without any bottleneck or such. But drive I am having is a WD Green.
I"m not concerned about the drive being 2TB, but the drive being WD black.
It is much faster than other drives, and one of the very few drives which really 'needs' 6gbps sata connector.