They are not, says studies ! it says they have no effect, and at worst, they seriously degrade performance. Although gaining more available memory might seem beneficial, it isn't. As RAM Optimizers force the available-memory counter up, they force other processes' data and code out of memory !!! you may have noticed, that after using a ram optimizer, it does take time for aplication to re- or cold- start ! for just-closed applications, they may however help in unloading their dll's.
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*mywebpages.comcast.net/SupportCD/XPMyths.html