Ok there is a cure so listen tight( note there are some bugs)
Speak to Raminus Polus in the Arcane University in the Imperial City and ask about the Vampire Cure. He will tell you about the Count of Skingrad also being a vampire and that you might want to speak to him.
Speaking to the Count continues the quest. The Count will tell you about a witch who is the last of her kind. Legend has it they were able to cure Vampirism. He will also tell you where to find this witch.
Once you have spoken to the witch, she will ask for 5 empty Grand Soul Gems before she will help you. The soul gems may be purchased from certain members in the mages guilds. Felen in Anvil; Ardaline in Bravil; Selena in Bruma; Eilonwy in Cheydenhal; Angalmo in Chorrol; and Alves in Leyawiin. You can of course also try to steal them from various display cases located around in the various guilds.
On returning to the witch, she will require the following items from you: Two Bloodgrass shoots, six cloves of Garlic, five Nightshade leaves, the blood of an Argonian and the ashes of a powerful vampire.
Two Bloodgrass: This is the tall red grass you see everywhere in Oblivion, so is easy to find. "The Main Ingredient" in the Imperial City and Sinderion (The West Weald Inn, in Skingrad) sells them too.
Six cloves of Garlic: Many homes have these lying around on the dinner table or stacked somewhere else. Try some homes in Skingrad.
Five Nightshade leaves: You can find some southwest of Skingrad. You can also find some at "The Main Ingredient" in the Imperial City.
Blood of an Argonian: You can get this from any Argonian (lizard people). Just stab one of them once with the special dagger you get from the witch and hope he doesn't report you. If you don't want a bounty: There is an Argonian at a Deadric Shrine on the south bank of the Silverfish River. (Where the letter R in "Silverfish River" is on your map). He is frozen and can't fight back thus you can stab without consequence.
Ashes of a powerful vampire: This 'powerful' vampire's name is Hindaril. Ask the witch about it and she will mark his location on your map. His home is a nesting ground for vampires but they die easily (especially with fire spells). If you still have trouble you could wait until you're in the fourth and final stage of being vampire and slaughter them like lambs.
Bug 1
Apparently there is a bug which may occur if you hand in the items in the wrong order which prevents you from completing the quest.
Your options then would be to reload a previous game or to type "set MS40.cureready to 1" into the console after you have given the ingredients to the witch. This will cause a new topic to appear and allows you to complete the quest properly.
Just hand in the items in the order I named them and this shouldn't happen.
Bug 2
If you give the witch the last ingredient and the order to brew to potion at 11 p.m., she will never return from the basement so you can’t get the potion from her.
To solve this problem either load an previous savegame and talk to her at a different time or type the following commands into the console (not at 11 p.m. or the bug will occur again!) and wait 24 hours:
"set MS40.currentday to GameDay"
"set MS40.currenthour to GameHour"
"set MS40.cureready to 3"
After you get them all and give them to the witch, she will give you two potions, one for you and one for the count's wife. Giving this to the count will earn you some gold.
Bug 3 (glitch)
After the quest reward is recieved, it is possible to keep pressing the reward topic to recieve the reward over and over again. It is possible to return to the count later and do this anytime, even after the quest is completed. There does not seem to be any limit to the amount of gold you can amass.
Level
Reward
1-4
250
5-9
500
10-14
1000
15-19
2500
20-24
5000
25-29
7500
30+
10000
Bug 4: I discoverd that sometimes when you talk to her the option of handing in the bloddgrass doesnt appear I handed in everthing else and bloodgrass isnt their, and yes i did have them in my inventory. So watch out for that.
Note : taken from gspot\