I can't live without my wireless keyboard/mouse. The freedom is enormous, and it's not just 2 meters either. I can operate my keyboard from well over 7 meters, although it's not necessary. The absence of clutter is another boon, because I have enough wires all over the place already.
The drawbacks are that the battery changing is irritating, and has to happen fairly often. Newer models tell you how much juice they have left, but their accuracy is debatable. Quite a few times I've found my keyboard out of power, and I can't do a thing about it. The other drawback, is in getting a bluetooth keyboard. Although they may have some advantages, they don't work well in pre-boot environment, so you may have some trouble. However this doesn't happen with non-bluetooth wireless keyboards, so they're ideal.