there cant be compatibility issues between speakers and sound cards
atleast i dun think so
just that u'll be usin 5.1 speakers on a 6.1/7.1 card
anyways this is suave_guy's department ....
wait for him
"The product is not compatible with a Creative Audigy 2 sound card. The connection cable that is provided to link to the decoder connects 2 incompatible plugs. So when watching DVD or playing surround games you lose the sound in the rear boxes. I found a thread on the Creative forums where someone explains it is a design problem, the solution is to bypass the decoder and put the box plugs directly in the soundcard. (Though the system works correctly with a XBOX or DVD apparently.) I only recently bought a Creative Audigy 2, just to be able to enjoy the sound I was missing... now I must buy another speakerset! "